Endocrine Abstracts

Aim: Low BMD and atherosclerosis may share similar underlying biological mechanisms including higher serum phosphate and inflammation. Neutrophil-lymphocyte ratio (NLR) as a simple marker of inflammation. There are scarce data indicating improved atherosclerosis and cardiovascular events with biphosphonate and teriparatide therapy. We aimed to evaluate NLR before and after 6 months of teriparatide therapy in patients with severe established osteoporosis....

Introduction: Primary hyperparathyroidism is the most common cause of hypercalcemia in the general population. Hypercalcemia during pregnancy can result in significant maternal and fetal morbidity and mortality.Case: A 30-year-old pregnant female primigravida in the 31 weeks of gestation with complaint of obstinate constipation was admitted to our emergency department. In laboratory tests, hypercalcemia was detected. She was a Syrian refugee and was unab...

Introduction: Platelets and neutrophils take part in proliferation of cancer cells, angiogenesis, and metastasis. Studies on various cancer types showed relation between prognosis and absolute numbers of neutrophils, lymphocytes, and the ratio in-between (NLR) and platelet/lymphocyte ratio (PLR). We aimed to evaluate NLR and PLR and their relation with features of differentiated thyroid carcinoma (DTC).Materials and methods: Electronic data of 330 patien...

Introduction: Fibrates are widely used to manage dyslipidemia but these drugs can induce rhabdomyolysis with acute renal failure. Rhabdomyolysis is a skeletal muscle cell damage condition associated with the release of toxic components of the cells and to the end;renal failure. The onset of rhabdomyolisis can extend to 6 months with fibrate therapy. Some researchers purpose that the influenza vaccıne can induce the rhabdomyolisis in patients who receive myotoxic drugs.Her...

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...

Seckel syndrome (SS) is described as the prototype of the primordial bird-headed type of dwarfism (Seckel 1960). It represents a spectrum of multisystem abnormalities. We present a case of SS and discuss the possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 Diabetes Mellitus (DM) and severe insulin resistance (IR).Case: A 21-year-old female was referred to our clinic because of growth retardation and amenorrhea. At birth, s...

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

Aim: Neopterin has been found to be associated with disease activity in various infectious, inflammatory, and autoimmune diseases. It is an indicator of immune response as it is released after activation of monocytes and macrophages by IFN-γ. It was aimed to measure neopterin levels in Graves’ disease, which is a T cell-mediated autoimmune disease of the thyroid gland.Materials and Methods: Twelve healthy individuals (6 women, 6 men), 13 Graves...

Objectives: Disorders concerning the endocrine system may be seen in patients with transfusion-dependent thalassemia major. It is thought that iron accumulated in the organs, especially with transfusion, causes this. In our study, we tried to reveal a relationship by comparing the iron parameters of these patients with various endocrine parameters.Methods: Our study is a retrospective study.The data of 18 thalassemia major patients who applied to Osmanga...

Introduction: Pituitary apoplexy (PA) is a clinical emergency resulting from acute ischemia or bleeding of the pituitary gland. Complaints of patients are usuallay headache and vision problems. We tried to discuss the reasons for presentation, pituitary imaging and hormones of patients.Patients and Methods: 10 patients (5 men and 5 women), median age 53 years at diagnosis were retrospectively reviewed. FSH, LH, estradiol/testosterone, GH, IGF1, TSH, FT4,...